Researchers in the US say that they’ve found that the brain can adapt to depression treatments better than people, potentially helping people overcome the symptoms of the disease.
Key points:Brain-imaging research suggests that people with depression experience more impairment than people who do not suffer from the diseaseThe study suggests that a lack of a normal sleep cycle may contribute to this differenceThe results are published in the journal Molecular Psychiatry.
The researchers recruited mice to be treated with a combination of antidepressant drugs, a form of sleep deprivation, and a light-dark cycle.
They also had a small group of healthy mice on an artificial light cycle.
After five weeks, they found that depressed mice showed a significant improvement in brain function.
In mice that were treated with antidepressants, the mice did better than mice that had not been treated with the drugs.
“The drugs, combined with the light-cycle regime, had the greatest effect in improving the brains of depressed mice,” the study’s lead author, Dr Mariana Martinez-Martinez, told the New York Times.
“That is, the depression-induced depression treatment caused them to lose their ability to process sensory information, and this in turn caused the loss of memory.”
We know that when we suppress these receptors, we decrease our ability to learn and remember.
“Martinez-Martez, who is also an assistant professor of medicine at Johns Hopkins University, said that this result is particularly promising because of the fact that it was based on mice, and not humans.”
These mice are the best model that we have for depression, because they’re in a well-controlled environment,” she said.”
If you look at a lot of other diseases, you don’t see this kind of effect.
“The researchers say that while this may seem like a minor improvement, it is a “significant change” in mice, because the mice’s brains are “quite similar” to those of people with the disease, and they have the same “episodic memory and behavioral patterns”.
It is not clear how depression affects the brain in humans.
A 2015 study in the British Medical Journal found that people who have been diagnosed with depression do not experience the same loss of cognitive function as those who do NOT suffer from depression.
Martinez says that while there may be differences between people with and without depression, the researchers believe that “we do not see a direct relationship between the two”.
The study involved four mice, but the researchers hope that more studies will be conducted to confirm the findings.”
There’s no evidence that it’s a causal relationship, but it does seem that the mice were able to adapt to the light cycle in a way that may help them recover their ability in terms of their cognitive abilities,” Martinez-Martin said.
The study was supported by the National Institutes of Health and the US National Institute of Mental Health.